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Jens Waldmann Selected Research

Islet Cell Adenoma (Islet Cell Tumors)

1/2014Inhibition of heat shock protein 90 with AUY922 represses tumor growth in a transgenic mouse model of islet cell neoplasms.
3/2012Epithelial-mesenchymal transition is a critical step in tumorgenesis of pancreatic neuroendocrine tumors.
1/2012Sorafenib inhibits tumor growth and improves survival in a transgenic mouse model of pancreatic islet cell tumors.
11/2011Hedgehog inhibition with the orally bioavailable Smo antagonist LDE225 represses tumor growth and prolongs survival in a transgenic mouse model of islet cell neoplasms.
3/2011Hedgehog inhibition with cyclopamine represses tumor growth and prolongs survival in a transgenic mouse model of islet cell tumors.

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Jens Waldmann Research Topics

Disease

27Neoplasms (Cancer)
10/2019 - 01/2006
7Pancreatic Neoplasms (Pancreatic Cancer)
01/2018 - 05/2010
5Islet Cell Adenoma (Islet Cell Tumors)
01/2014 - 03/2011
3Adrenocortical Carcinoma
10/2019 - 10/2014
3Neoplasm Metastasis (Metastasis)
01/2018 - 03/2011
2Carcinogenesis
01/2016 - 04/2009
2Cushing Syndrome
01/2016 - 10/2014
2Hyperplasia
10/2014 - 04/2009
2Carcinoid Tumor (Carcinoid)
01/2014 - 09/2007
2Multiple Endocrine Neoplasia Type 1
02/2013 - 11/2008
2Zollinger-Ellison Syndrome (Syndrome, Zollinger-Ellison)
12/2011 - 07/2009
1Metaplasia
01/2018
1Disease Progression
01/2016
1Adenoma (Adenomas)
10/2014
1Chronic Pancreatitis
06/2014
1Inflammation (Inflammations)
06/2014
1Systemic Inflammatory Response Syndrome (Sepsis Syndrome)
06/2014
1Adenocarcinoma
06/2014
1Pancreatic Fistula (Pancreatic Fistulas)
10/2013
1Exanthema (Rash)
10/2013
1Gastrinoma
02/2013
1Lung Neoplasms (Lung Cancer)
07/2012
1Adenocarcinoma of Lung
07/2012
1Primitive Neuroectodermal Tumors (PNET)
03/2012
1Hypertension (High Blood Pressure)
11/2011
1Hyperparathyroidism
06/2011
1Chronic Renal Insufficiency
06/2011
1Thyroid Neoplasms (Thyroid Cancer)
03/2011
1Hyperinsulinism (Hyperinsulinemia)
07/2009
1Pheochromocytoma
07/2009
1Parathyroid Neoplasms (Parathyroid Neoplasm)
04/2009
1Parathyroid Diseases (Parathyroid Disorders)
04/2009
1Neuroendocrine Tumors (Neuroendocrine Tumor)
11/2008
1Diarrhea
07/2008
1Achlorhydria (Hypochlorhydria)
07/2008
1Hypokalemia
07/2008
1Vipoma (WDHA)
07/2008

Drug/Important Bio-Agent (IBA)

4Hormones (Hormone)IBA
10/2019 - 07/2009
4Cadherins (E-Cadherin)IBA
03/2012 - 09/2007
3Transcription Factors (Transcription Factor)IBA
01/2018 - 09/2007
2Biomarkers (Surrogate Marker)IBA
10/2019 - 06/2014
2C-Reactive ProteinIBA
03/2016 - 06/2014
2Hydrocortisone (Cortisol)FDA LinkGeneric
01/2016 - 10/2014
2Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA
01/2016 - 10/2014
2Proteins (Proteins, Gene)FDA Link
01/2016 - 07/2012
2DNA (Deoxyribonucleic Acid)IBA
01/2016 - 06/2009
2Matrix Metalloproteinases (MMPs)IBA
10/2014 - 07/2012
2GemcitabineFDA Link
06/2014 - 10/2013
2Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
10/2013 - 05/2010
2Pharmaceutical PreparationsIBA
09/2013 - 03/2012
2cyclopamineIBA
03/2011 - 09/2007
2Pancreatic Polypeptide (Pancreatic Polypeptide (PP))IBA
06/2009 - 07/2008
1SteroidsIBA
10/2019
1Gonadal Steroid Hormones (Sex Hormones)IBA
10/2019
1estradiol sulfateIBA
10/2019
1EstroneFDA Link
10/2019
1Tumor Biomarkers (Tumor Markers)IBA
10/2019
1Neuropeptide YIBA
01/2018
1CeruletideIBA
01/2018
1NeuropeptidesIBA
01/2018
1CateninsIBA
01/2016
1Estradiol (Delestrogen)FDA LinkGeneric
12/2015
1ProgesteroneFDA LinkGeneric
12/2015
1AndrogensIBA
10/2014
1Protein Isoforms (Isoforms)IBA
10/2014
1Dexamethasone (Maxidex)FDA LinkGeneric
10/2014
1Interleukin-6 (Interleukin 6)IBA
06/2014
1InterleukinsIBA
06/2014
1Heat-Shock Proteins (Heat-Shock Protein)IBA
01/2014
15- (2,4- dihydroxy- 5- isopropylphenyl)- 4- (4- morpholin- 4- ylmethylphenyl)isoxazole- 3- carboxylic acid ethylamideIBA
01/2014
1Erlotinib Hydrochloride (CP 358,774)FDA Link
10/2013
1Simvastatin (Zocor)FDA LinkGeneric
09/2013
1Snail Family Transcription FactorsIBA
03/2012
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
01/2012
1Sorafenib (BAY 43-9006)FDA Link
01/2012
1Antihypertensive Agents (Antihypertensives)IBA
11/2011
1sonidegibIBA
11/2011
1CreatinineIBA
11/2011
1AntimetabolitesIBA
03/2011
1Calcitonin (Calcitonin, Eel)FDA LinkGeneric
03/2011
1Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
05/2010
1EnalaprilFDA LinkGeneric
05/2010
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
05/2010
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
07/2009

Therapy/Procedure

9Therapeutics
03/2016 - 03/2011
2Lymph Node Excision (Lymph Node Dissection)
02/2013 - 01/2006
2Pancreaticoduodenectomy
02/2013 - 12/2011
1Drug Therapy (Chemotherapy)
06/2014
1Pancreaticojejunostomy
10/2013
1Adrenalectomy
11/2011
1Thymectomy
06/2011
1Renal Dialysis (Hemodialysis)
06/2011
1Parathyroidectomy
06/2011
1Vascular Surgical Procedures
11/2008
1Sternotomy
11/2008
1Combined Modality Therapy
11/2008
1Laparotomy
07/2008